Health News

Scientists at the University of Rochester pulled off a remarkable experiment: they transferred a longevity-related gene from the famously long-lived naked mole rat into mice, and the mice ended up healthier and lived longer. The special gene boosts production of a substance called high molecular weight hyaluronic acid, which appears to protect against cancer, reduce inflammation, and support healthier aging. The modified mice showed stronger resistance to tumors, healthier guts, and lower levels of age-related inflammation.

Scientists have uncovered a striking brain difference linked to psychopathy: people with psychopathic traits were found to have a striatum — a brain region tied to reward, motivation, and decision-making — that was about 10% larger on average than those without such traits. Using MRI scans and psychological assessments on 120 participants, researchers connected this enlarged brain region to thrill-seeking, impulsive behavior, and a stronger drive for stimulation.

Scientists have uncovered a hidden “stop-scratching” signal in the nervous system that tells your brain when enough scratching is enough. The discovery centers on a molecule called TRPV4, which acts like part of an internal braking system for itch relief. In experiments involving chronic itch similar to eczema, mice missing this signal scratched less often—but when they did scratch, they couldn’t stop.

Rebooting the gut microbiome with bacteria from youth may help stop aging-related liver damage and even prevent liver cancer, according to new research in mice. Older mice that received their own preserved youthful microbiome showed less inflammation, reduced DNA damage, and no signs of liver cancer. Researchers also found that the treatment suppressed a cancer-linked gene called MDM2, making older mice biologically resemble younger ones.

Researchers have developed a stem cell-based model of the human intestine that may transform how new IBD treatments are discovered. After testing thousands of compounds, they identified glycyrrhizin — a natural substance found in black licorice — as a promising anti-inflammatory candidate. In both lab-grown tissue and mice, the compound reduced intestinal damage and cell death linked to IBD.

A new study shows that listening to your own favorite workout music can dramatically boost endurance. Cyclists exercising with self-selected songs lasted nearly 20% longer than when riding in silence, yet they didn’t feel more exhausted at the end. Researchers say music may help people stay in the “pain zone” longer without increasing perceived strain.

Scientists studying axolotls, zebrafish, and mice have uncovered a shared set of genes that may one day help humans regrow lost limbs. By identifying powerful “SP genes” involved in regeneration, researchers discovered that disabling these genes stopped proper bone regrowth in salamanders and mice. They then used a gene therapy inspired by zebrafish biology to partially restore regeneration in mice, marking a major step toward future treatments that could replace damaged limbs with living tissue instead of prosthetics.

Scientists have uncovered a surprising secret hidden inside fat cells that could reshape how we think about obesity and metabolic disease. A protein called HSL, long believed to simply release stored fat when the body needs energy, turns out to have a second job deep inside the nucleus of fat cells—helping keep those cells healthy and balanced. Even more surprising, people and mice missing this protein don’t become obese as expected; instead, they lose fat tissue in a dangerous condition called lipodystrophy.

A common constipation drug may have unexpectedly unlocked a new way to slow chronic kidney disease — a condition that affects millions and often leads to dialysis. In a clinical trial involving 150 patients, researchers found that lubiprostone, a medication normally used to treat constipation, helped preserve kidney function in people with moderate CKD. Scientists traced the effect to changes in gut bacteria that boosted production of spermidine, a compound linked to healthier mitochondria and reduced kidney damage.

Scientists have uncovered a surprising way to influence the bacteria living in our mouths — not by killing them, but by interrupting how they “talk” to each other. Researchers found that dental plaque bacteria use chemical signals to coordinate growth, and by blocking those signals, they were able to encourage healthier bacteria while reducing disease-linked microbes tied to gum disease. Even more intriguing, the bacterial conversations changed depending on oxygen levels above and below the gums, revealing an entirely new layer of complexity inside the mouth.