Health News

Scientists have discovered that some severe genetic disorders linked to rapid aging may be driven not just by damaged DNA, but by the body’s overreaction to that damage. When broken DNA fragments leak into the wrong part of a cell, an immune sensor called cGAS can mistake them for signs of a viral infection, triggering chronic inflammation and even interfering with DNA repair itself.

Eating four to six servings of whole grains a day may deliver meaningful benefits for heart health, according to a large review of 87 clinical trials. Researchers found improvements in body weight, waist size, blood pressure, cholesterol, blood sugar, triglycerides, and some markers of inflammation.

Scientists reconstructed videos from the brain activity of mice, producing 10-second clips based only on signals from neurons in the visual cortex. The breakthrough could help reveal how the brain reshapes what we see before it becomes our perception of reality.

Eating more ultra-processed foods was linked to greater fat buildup inside thigh muscles, according to MRI scans of 615 adults at risk for knee osteoarthritis. Surprisingly, the association remained even after researchers accounted for calorie intake, physical activity, and other factors. Fatty changes in these muscles may weaken support around the knee and potentially increase osteoarthritis risk.

A naturally occurring molecule called erucamide may help the retina fight back against diseases that cause progressive vision loss. Restoring the molecule activated protective immune responses that helped stabilize retinal tissue and slow aspects of degeneration in preclinical models.

Older adults who changed the balance of fat, carbohydrates, and animal protein in their diets showed signs of reduced biological age after just four weeks. The strongest result appeared in participants eating an omnivorous, lower-fat, higher-carbohydrate diet.

Simply smelling chocolate helped men complete more leg extension repetitions without making the workout feel harder, with dark chocolate producing the strongest effect. The researchers think familiar food aromas may influence appetite and motivation by making the brain anticipate eating.

Scientists have uncovered sweeping changes in how the human brain controls and organizes its genome beginning in midlife, offering new clues to why aging sharply increases the risk of Alzheimer’s and other neurodegenerative diseases. One of the biggest shifts occurred between about ages 50 and 75, when many of the brain’s original immune cells declined and were replaced by cells with more inflammatory characteristics. Researchers also found weakening of cells that help maintain the blood-brain barrier, along with widespread deterioration in the genome’s three-dimensional organization.

The flesh eating New World screwworm has returned to the United States, threatening livestock, wildlife, pets and potentially people as it spreads north. A new UC San Diego tracking system aims to predict where the parasite could strike next while officials revive the eradication strategy that defeated it decades ago.

A major analysis of 139 clinical trials involving nearly 10,000 people suggests that some of the simplest treatments may work best for knee osteoarthritis. Knee braces ranked highest overall for reducing pain, stiffness, and mobility problems, while water-based therapy was especially effective for pain and regular exercise consistently improved both pain and physical function. More high-tech approaches, including ultrasound, generally performed worse.