June 2, 2023

In past centuries before modern seizure medicines were developed, people with epilepsy and their doctors looked for a remedy in various herbs and combinations of herbs. Occasionally they found one that seemed to help. None of these remedies have been proven to be safe and effective. Unfortunately, some of them can make seizures worse by causing seizures, or by interacting with prescription seizure medications. Even though some herbal medicines are available as dietary supplements, they are not necessarily safe for people with epilepsy, just because they’re “natural.”
This is not to say that if you have epilepsy you must avoid every herb, down to that little piece of parsley on the side of your plate. There are hundreds of possible herbal remedies, and our knowledge of their effects is far from complete. Testing a potential medication in a controlled way in a large number of people is an expensive venture. Little research of this kind has been done with herbs, but it’s beginning to happen now. For example tests are being done on an ingredient that is related to medical marijuana, and another that comes from a Chinese moss plant.
Even when we do have some information on a particular herb, it can be difficult to apply. The forms, dosages, and combinations in which herbs are sold are not well standardized in the United States. As long as the manufacturer does not claim that the herb will cure or prevent a particular medical condition, the Food and Drug Administration (FDA) considers it a “dietary supplement” and regulates it much less strictly than other medications.
A complicating factor is that people with epilepsy may get undesirable effects from an herb or herbal combination that is safe for most others. It appears that a few herbs (including some common ones) may directly increase the chance of seizures. Many others can interact with seizure medicines, either causing more seizures or worsening side effects. Of course the effect is different depending on what kind of seizures you have and what seizure medicines you take.
If you are thinking of trying an herbal medicine because you don’t like your current epilepsy treatment or because you’ve heard that it might help with some other problem (like depression, sleep, memory loss, or PMS), read on.
Definitely! Take the information that you gather to your doctor. If you’re having seizures or unacceptable side effects, tell the doctor how you feel (remember to take your seizure calendar) and ask whether there’s some other treatment that is likely to help you. When you say that you’ve been investigating an herbal medicine, the doctor should be willing to hear you out. Doctors also are trying to get educated about herbal products, so the doctor may or may not have more information about that herb.
Much of the information in this article is based on Spinella M: Herbal medicines and epilepsy: The potential for benefit and adverse effects. Epilepsy Behav 2001; 2(6):524-532. (PMID 12609386)
Authored By:

Patty Obsorne Shafer RN, MN
Steven C. Schachter, MD

Reviewed By:

Joseph I. Sirven MD / Patricia O. Shafer RN, MN

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